TAMISTOL® – A SIMPLE SOLUTION FOR SENSITIVE PROBLEMS

TAMISTOL® (over-the-counter medicinal product) is the only Miramistin in suppository form available in Ukraine, designed for effective treatment of infections in the female reproductive system.

Composition of the Medicinal Product:

Active ingredient: Miramistin

Each suppository contains 0.015 g of Miramistin.

Pharmacological Group: Antimicrobial and antiseptic agents used in gynecology, excluding combinations with corticosteroids.

ATC Code: G01A

Mechanism of Action:

TAMISTOL® is an antimicrobial drug (antiseptic). Its active ingredient, Miramistin, is a cationic surface-active agent with antimicrobial properties. The action mechanism of Miramistin involves direct hydrophobic interaction of its molecules with the lipids in microbial cell membranes, leading to membrane fragmentation and destruction.

Unlike other antiseptics, Miramistin demonstrates high selectivity for microorganisms and has minimal effect on human cell membranes due to their unique structure (longer lipid radicals in human cells limit hydrophobic interaction with Miramistin).

Miramistin exhibits strong antimicrobial activity against:

• Gram-positive and Gram-negative bacteria (aerobic and anaerobic), spore-forming and non-spore-forming bacteria, as monocolonies or microbial associations, including hospital strains resistant to antibiotics.
• Pathogens of sexually transmitted infections (Neisseria gonorrhoeae, Treponema pallidum, Trichomonas vaginalis, Chlamydia spp.), as well as herpes viruses, HIV, and others.
• Fungi, including Candida albicans, Candida krusei, dermatophytes (Trichophyton rubrum, Microsporum canis), and other pathogenic fungi (Malassezia furfur), including those resistant to chemotherapeutic agents.
• Miramistin also reduces microbial resistance to antibiotics and exhibits anti-inflammatory effects. It enhances local protective reactions, promotes regeneration processes, and activates immune defense mechanisms without affecting hormonal balance.

Contraindications:

• Individual sensitivity to the components of the product.
• Intravaginal use during pregnancy (safety has not been studied).

Special Precautions:

• The effectiveness of the product depends on adherence to the instructions for use:
• Insert the suppository as deeply as possible into the vagina/rectum.
• Avoid using soap or soap-based products for genital hygiene 2 hours before and 2 hours after intravaginal administration. Use only clean water for this purpose.
  

Side Effects: In rare cases, a brief sensation of burning may occur, which disappears within 15-20 seconds and does not require discontinuation of treatment.

Category of Sale: Over-the-counter.

Storage Conditions: Keep out of reach of children.